Hi, I'm Dr Sachin Jadhav

MD, DM (Clinical Hematology)

Director of Hematology and Bone Marrow Transplant (BMT) Kamineni Gem Care Group

CEO OF CHIRON CANCER CARE Chairman, International Hematology Consortium

Bone Marrow Transplant

Bone marrow transplant is a medical procedure that replaces the destroyed or damaged bone marrow cells with healthy bone marrow cells. It involves the extraction of healthy bone marrow cells, filtration and transferring them back to the donor itself (Autologous Transplant) or to another individual, who is called the recipient. (Allogenic Transplant)

Why is Bone Marrow Transplant required?

The goal of bone marrow transplant is to improve quality of life and cure many benign diseases and a few types of cancer successfully. For some diseases, a bone marrow transplant serves as the only potential cure.

A bone marrow transplant becomes necessary when:

The existing bone marrow cells are damaged, destroyed or not functioning optimally due to health conditions such as aplastic anaemia, leukaemia, etc. A bone marrow transplantation in this case helps patients have a healthy, functioning marrow.
The immune system needs to be regenerated to fight the existing or residual cancers that could not be treated completely with radiation or chemotherapy.

Treatments Available for following conditions:-

Malignant Haematological Disorder/Blood Cancers

Malignant Haematological Disorder/Blood Cancers
Benign Haematological Disorders

Leukaemia

Leukaemia is a form of blood cancer wherein the bone marrow makes many white blood cells that aren’t normal and produces too many which get into the bloodstream. Major types of leukaemia are AML, ALL, CML & CLL.

Lymphoma

This cancer begins in infection-fighting cells and is largely present in the lymph nodes, spleen, thymus, bone marrow. There are over 60+ types of lymphoma; however, it is broadly classified into two types – Hodgkin’s Lymphoma (HL) & Non-Hodgkin’s Lymphoma (NHL).

Myeloma

Myeloma occurs in plasma cells, a type of white blood cell. This cancer affects and damages the bones, immune system, kidneys and red blood cell. Multiple Myeloma is the most common type of myeloma.

Red Blood Cell (RBC) Disorders

Red blood cell disorders are those that affect the red blood cells, whose key function is to carry oxygen to various parts of the body. Common red blood cell disorders include Sickle Cell Anaemia, Aplastic Anaemia and Thalassaemia.

White Blood Cell (WBC) Disorders

Platelets have a significant role in homeostasis and wound healing. In the case of platelet disorders, either the number of platelets increases or decreases or the functioning of the platelets is affected. Some of the major platelet disorders include ITP and Dengue.

Platelet Disorders

Bleeding Disorders

In the case of bleeding disorders, when an injury occurs, the blood does not clot, which will eventually lead to various complications ranging from mild to severe. Haemophilia is one of the common bleeding disorders.

Clotting Disorders

In the case of clotting disorders, the blood clots unexpectedly in the veins and arteries and affects the blood flow and functioning of the organs. If the clot occurs in legs, it is known as Deep Vein Thrombosis (DVT) and if it occurs in the lungs, it is known as Pulmonary Embolism.

Haematology & Bone Marrow Transplantation

Haematology and bone marrow transplantation department is a well-equipped unit of experienced and skilled haematologists and BMT experts who are specialised in the diagnosis and management of a wide range of benign and malignant disorders of blood and bone marrow.

Years of Experience in Haem-BMT

Bone Marrow Transplants

Patients of blood cancers

Created BMT Departments

My Professional Work

Dr. Sachin Jadhav is presently the Director of Hematology and Bone Marrow Transplantation (BMT) at Kamineni Gem Care Group. With extensive experience in founding and managing BMT centers, he has successfully established 14 such centers since 2013. Additionally, Dr. Jadhav serves as the CEO of Chiron Cancer, where he focuses on creating accessible cancer and BMT facilities across multiple countries. He plays an active role in several prestigious professional organizations, including ASTCT, ASH, and AAAS, and holds various leadership positions such as International Ambassador for the CGC.

Hematopoietic Transplant Centers

Establishing New Hematopoietic Transplant Centers

Since February 2012, Dr Sachin have successfully developed the following Hematology-Stem Cell Transplant Programs:

– BGS Global Hospital, Bengaluru
– Global Hospital, Mumbai
– Global Hospital, Chennai
– Fortis Hospital, BG Road, Bengaluru
– Meitra Hospital, Calicut
– HCG Hospital, KR Road, Bengaluru
– HCG Hospital, Borivali, Mumbai

Consultancy for Upcoming Programs:

– LabAid Hospital, Dhaka
– Lanka Hospital, Colombo, Sri Lanka

Dr. Sachin Jadhav leads an experienced team comprising:

– Hematologists and BMT Physicians
– Nursing Head (Hematology and BMT)
– Nursing Educator (Hematology and BMT)
– Quality Manager (Hematology and BMT)
– BMT Coordinator
– Business Development (Hematology and BMT)
– Clinical Pharmacology and Clinical Research specialists

Together, we coordinate the recruitment of transplant physicians, junior doctors, and nurses, oversee infrastructure development, and plan the acquisition of biomedical equipment, including apheresis devices. We train teams on Standard Operating Procedures (SOPs) and policies, implement a comprehensive Quality Management Plan, and provide ongoing support to ensure the new program’s smooth transition and operational efficacy.

Principal Investigator
o Optical Genome Mapping for hematologic disorders
o Open-labelled randomized controlled trial of Sitagliptin with or without ATG and post-transplant cyclophosphamide for GVHD prophylaxis
o Open labelled randomized controlled trial of meropenem versus ceftazidime avibactum versus ceftazidime avibactum with aztreonam as first line therapy for high-risk febrile neutropenia
o Open labelled randomized controlled trial of romiplostim for promoting early marrow recovery in hematopoietic stem cell transplantation
o MATRix protocol for the treatment of primary CNS lymphoma in low- and middle-income countries
o Analysis of bronchoalveolar lavage fluid in febrile neutropenia
o Efficacy of granulocyte transfusions in high-risk febrile neutropenia

o Fellowship in Leukemia/BMT at
– Fortis Hospital, Bengaluru
– HCG Hospital, KR Road, Bengaluru Kamineni Cancer Center, Hyderabad

o DNBE (Clinical Hematology) at
-HCG Hospital, KR Road, Bengaluru

-Kamineni Cancer Center, Hyderabad

My Professional Work

Hematopoietic Transplant Centers

Establishing New Hematopoietic Transplant Centers

Since February 2012, Dr Sachin have successfully developed the following Hematology-Stem Cell Transplant Programs:

– BGS Global Hospital, Bengaluru
– Global Hospital, Mumbai
– Global Hospital, Chennai
– Fortis Hospital, BG Road, Bengaluru
– Meitra Hospital, Calicut
– HCG Hospital, KR Road, Bengaluru
– HCG Hospital, Borivali, Mumbai

– BGS Global Hospital, Bengaluru
– Global Hospital, Mumbai
– Global Hospital, Chennai
– Fortis Hospital, BG Road, Bengaluru
– Meitra Hospital, Calicut
– HCG Hospital, KR Road, Bengaluru
– HCG Hospital, Borivali, Mumbai

Consultancy for Upcoming Programs:

– LabAid Hospital, Dhaka
– Lanka Hospital, Colombo, Sri Lanka
Team Members

Dr. Sachin Jadhav leads an experienced team comprising:

– Hematologists and BMT Physicians
– Nursing Head (Hematology and BMT)
– Nursing Educator (Hematology and BMT)
– Quality Manager (Hematology and BMT)
– BMT Coordinator
– Business Development (Hematology and BMT)
– Clinical Pharmacology and Clinical Research specialists

Together, we coordinate the recruitment of transplant physicians, junior doctors, and nurses, oversee infrastructure development, and plan the acquisition of biomedical equipment, including apheresis devices. We train teams on Standard Operating Procedures (SOPs) and policies, implement a comprehensive Quality Management Plan, and provide ongoing support to ensure the new program’s smooth transition and operational efficacy.
Research Project

Principal Investigator
o Optical Genome Mapping for hematologic disorders
o Open-labelled randomized controlled trial of Sitagliptin with or without ATG and post-transplant cyclophosphamide for GVHD prophylaxis
o Open labelled randomized controlled trial of meropenem versus ceftazidime avibactum versus ceftazidime avibactum with aztreonam as first line therapy for high-risk febrile neutropenia
o Open labelled randomized controlled trial of romiplostim for promoting early marrow recovery in hematopoietic stem cell transplantation
o MATRix protocol for the treatment of primary CNS lymphoma in low- and middle-income countries
o Analysis of bronchoalveolar lavage fluid in febrile neutropenia
o Efficacy of granulocyte transfusions in high-risk febrile neutropenia
Training Programs

o Fellowship in Leukemia/BMT at
– Fortis Hospital, Bengaluru
– HCG Hospital, KR Road, Bengaluru Kamineni Cancer Center, Hyderabad

o DNBE (Clinical Hematology) at
-HCG Hospital, KR Road, Bengaluru

-Kamineni Cancer Center, Hyderabad
Services

Problem With Blood Cells:

1. Low or High Hemoglobin, WBC or Platelets

• Thalassemia Sickle Cell Anaemia
• Immunodeficiency Syndrome

2.Coagulation

• Hemaphilia including surgeries in people living with hemophilia
• Platelet Function Disorders
• Rare Coagulation Disorders

3.Bone Marrow Issues
• Aplastic Anaemia
• MDS
• Myelofibrosis

4.Blood Cancers
• Leukemia
•Lymphoma
• Myeloma
• Blood and Marrow Transplant (BMT)i.e., Steam Cell Transplant

Medical Qualifications

Clinical Attachment Great Ormond Street Hospital, London, UK - 2013

Fellowship (Leukemia/BMT) University of British Columbia, Vancouver, Canada - 2012

DM (Clinical Hematology) CMC, Vellore - 2011

MD (Internal Medicine) BJ Medical College, Pune - 2004

MBBS Rajiv Gandhi Medical College, Thane - 2001

Management Qualifications

PhD Management Sciences Amrita School of Business, Bengaluru - Ongoing

Strategic Change Management IIM, Bangalore 2021

Mastering Design Thinking MIT Sloan 2021 MIT Sloan - 2021

Management Essentials Harvard Business School - 2021

My Work Experience

Dr. Sachin Suresh Jadhav is a highly esteemed professional in the field of Hematology and Blood and Marrow Transplantation (BMT).

Chairman

Marrow Matters Pvt. Ltd.

October 2017 to present

Group Head

HCG Group of Hospitals

August 2019 to Jan 2024

Consultant Hematology and BMT

Meitra Hospital, Calicut

April 2019 to July 2019

Consultant Hematology and BMT

Fortis Hospitals, Bengaluru

October 2017 to May 2019

Group Incharge Hematology and BMT

Global Hospital Group, India

February 2013 to October 2017

My Publications

1. Basavaraj A., Sachin Suresh Jadhav. Familial hypercholesterolemia presenting as intracranial xanthoma. A case report Journal of the Association of Physicians of India. 2006

2. AuroViswabandya and Sachin Suresh Jadhav. Management of classical Hodgkin lymphoma: utility of PET scanning. APICON Medicine Update, 2009, Edited by A.K. Agarwal, vol. 19, part II: 950-954.

3. AuroViswabandya and Sachin Suresh Jadhav.Extracting maximum from cytogenetics in acute leukemia. Haematology Update, 2008, Edited by Prof. MB Agarwal.

4. Ezhilarasi Chendamarai, Ansu Abu Alex, Saravanan Ganesh, Kavitha M Lakshmi, Sachin Suresh Jadhav, MD, Biju George, MD, Aby Abraham, MD, Poonkuzhali Balasubramanian, PhD, Shaji Ramachandran, PhD, Alok Srivastava, MD and Vikram Mathews, MD. Evaluation of mechanisms of resistance to Arsenic Trioxide in patients with acute promeylocytic leukemia. Blood. Volume 116, Issue 21, 19 November 2010.

5. Madhura Gangaiah, Divya Patil, Sangeetha D R, Dr. Andhe Pallavi, Dr. Sachin Suresh Jadhav, Dr. Jayanthi Thumsi. A Handy Diagnostic Tool for Preventive Therapy based on Prior Estimation of Metastasis. International Journal of Science and Research. Volume 4 Issue 2, February 2015.

More Publications

6.Mathangi J, Vishal Rao US, Kavitha ML, Subathira B, Mahadev Potharaju, Sachin Suresh Jadhav. Association of EGFR Overexpression and Habits Like Smoking, Alcohol, Tobacco or Betelnut Chewing in Head and Neck Squamous Cell Carcinomas. International Journal of Cancer Research, ISSN: 2051-784X, Vol.49, Issue.2: 1704-1710.

7. Jayanti Thumsi, M. Nataraj, ML Kavitha, Sachin Suresh Jadhav. Outcomes in financially disadvantaged patients with breast cancer in South India. JCO. 2014, 32,no. 15_suppL.

8. Jayanti S. Thumsi, Mallika Nataraj, Kavitha ML, Sachin Suresh Jadhav. Worse event-free and relapse-free survival in financially disadvantaged patients with breast cancer in South India. Journal of Cancer Policy. Sept 2017, Vol 13: 75-80

9.Jadhav S, Rajashekaraiah M, Chakraborty D, Bharath N, Sharieff SU, Vignesh G, et al. Retrospective analysis of 34 febrile neutropenia episodes – Role of a commercially available multiplex PCR in diagnosis of infection and its therapeutic implication in hemato-oncologic patients. Indian J Cancer 2021, 58(4): 501-510.

10. Vishal Rao US, Shalini Thakur, Jyothsna Rao, Gururaj Arakeri, Peter A Brennan, Sachin Jadhav, Mufti Suhail Sayeed, Gururaj Rao. Mesenchymal Stem Cells -Bridge Catalyst Between Innte And Adaptive Immunity In Covid 19. Medical Hypothesis. https://doi.org/10.1016/j.mehy.2020.109845

11. Dixit S, Jagadeesan MK, Jadhav S, Chikkarangappa R. Acute hematogenous E. coli osteomyelitis of bilateral tibia in chronic immune thrombocytopenic purpura. Saudi J Health Sci 2015;4:132-4.

12. Sachin SJ, Shalaka S, Goutham KJ, Smruthy AM, Anjali M, Priyank T, Hrishi V, Amey CP, Nishit and Shivakumar. Cyclosporine Induced Mesial Temporal Sclerosis – A Case Report. Indian J Neurol. 2021;2(1): 104.

13. Sachin SJ, Jyothi Goutham Kumar, Priyank Tripathi, et al. A prospective, observational study of dexamethasone induced hiccups in chemotherapy patients. International Journal of Current Pharmaceutical and Clinical Research. 2021, 11 (2): 39-42.

14. Sachin SJ, Smruthy AM, Goutham KJ, Shalaka S, Anjali M, et al. A Rare Case of Aspergillus Spondylodiscitis In B-Cell Acute Lymphoid Leukemia. J Orthopedics Rheumatol. 2021; 8(1): 2

15. Aswathy Asokan AN1, Sachin SJ, Chaitra P, Jemy AM, Aradhana KM, Manjula MB, Roselet J, Goutham KJ, Lakshmi A and Saranya UB. Nursing-Specific Management on Toxic Epidermal Necrolysis (Ten) In Cml Patient: Case Report. J Clin Investigat Dermatol. April 2022 Volume 10, Issue 1 5

16. Jadhav SS, Kumar JG, Tripathi P, Matani A, Ganesan SK, Vishnupriya, et al. Febrile neutropenia: An unusual cause of Pantoea agglomerans bacteremia in acute myeloid leukemia. J Precis Oncol 2022; 2: 49-51.

17. Mathivanan, V., et al. “Oral domiciliary therapy of multiple myeloma with cyclophosphamide, pomalidomide and dexamethasone regimen in the covid era: A pilot study.” Indian Journal of Hematology and Blood Transfusion (2020): S140 S140.

18. Amrit Kaur Kaler, Shaila1, R. Ashwini, R. Veena1, Sachin Jadhav, Baby Dharman, Ramesh Patil, Gautam Balaram, Prassana Kumari, Mithua Ghosh, Shruthi Sudarshan, B. S. Ajai Kumar. Molecular Profiling of Large B‑Cell Lymphomas: A Retrospective Observational Pilot Study. J Precis Oncol 2022; Volume 2 (2): 125-132.

19. Sandeep Rao; Kashish Dagli; Athira Sivadas; Sachin Suresh Jadhav. Botryoid neutrophil. ASH Image Bank. Sept. 2022. DOI https://imagebank.hematology.org/image/64316/botryoid-neutrophil?type=upload

20. Aswathy Asokan, Jadhav S, Badavath R. Novel Methodology for Assessing Nursing Competency in BMT Unit. Transplantation and Cellular Therapy. 2023 Feb 1;29(2):S432.

Get In Touch

Phone Number +91 9741351357

Email drsachinjadhav@hotmail.com

Address Amour, Villa 123, Valmark Cityville, Chandrashekharapura, Begur. Bengaluru 560076, India